Description

6-Amino-2-Chloromethyl-5-Cyano-4-(1-Ethyl-1 H-Pyrazol-4-Yl)-4 H-Pyran-3-Carboxylic Acid Ethyl Ester is a high-value, multi-functional heterocyclic building block with significant synthetic utility. Its complex molecular architecture, featuring pyran, pyrazole, amino, cyano, and ester functionalities, makes it a versatile intermediate for constructing advanced chemical libraries. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors. It serves as a critical precursor for the synthesis of novel active ingredients targeting a range of therapeutic and crop protection applications.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Chemical Synthesis Scaffold: Serves as a versatile precursor for creating diverse chemical libraries via further functionalization of its reactive amino, chloro, and cyano groups.
• Material Science Research: Potential intermediate in the development of specialty polymers, dyes, or functional materials due to its conjugated system and multiple reactive sites.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client-specific projects.

Basic Information

Product Name	6-Amino-2-Chloromethyl-5-Cyano-4-(1-Ethyl-1 H-Pyrazol-4-Yl)-4 H-Pyran-3-Carboxylic Acid Ethyl Ester
CAS No.	1005611-67-5
Molecular Formula	C16H17ClN4O3
Molecular Weight	348.79 g/mol
Synonyms	Ethyl 6-Amino-2-(chloromethyl)-5-cyano-4-(1-ethyl-1H-pyrazol-4-yl)-4H-pyran-3-carboxylate; 4H-Pyran-3-carboxylic acid, 6-amino-2-(chloromethyl)-5-cyano-4-(1-ethyl-1H-pyrazol-4-yl)-, ethyl ester; 6-Amino-2-chloromethyl-5-cyano-4-(1-ethylpyrazol-4-yl)-4H-pyran-3-carboxylic acid ethyl ester; CAS 1005611-67-5
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high purity. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We support development and scale-up projects with custom purity grades and regulatory documentation as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.