Description

n-Ethynyl-N,4-Dimethylbenzenesulfonamide is a specialized organic building block featuring a reactive ethynyl group and a sulfonamide moiety. This compound matters as a versatile intermediate for synthesizing more complex molecules, particularly in pharmaceutical and advanced material research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially those targeting specific enzyme inhibition.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, or plant growth regulators.
• Material Science: Serves as a monomer or cross-linking agent in the development of advanced polymers and functional materials.
• Chemical Synthesis: Acts as a versatile reagent in Sonogashira coupling and other palladium-catalyzed cross-coupling reactions.
• Academic & Institutional Research: Utilized in universities and research institutes for exploring new synthetic methodologies and reaction pathways.
• Ligand Precursor: Can be modified to create novel ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	n-Ethynyl-N,4-Dimethylbenzenesulfonamide
CAS No.	1005500-75-3
Molecular Formula	C10H11NO2S
Molecular Weight	209.26 g/mol
Synonyms	N-Ethynyl-4-methyl-N-methylbenzenesulfonamide; 4-Methyl-N-methyl-N-(2-propynyl)benzenesulfonamide; p-Toluenesulfonamide, N-ethynyl-N-methyl-; N-Methyl-N-(prop-2-yn-1-yl)-4-methylbenzenesulfonamide; N-Ethynyl-N-methyl-p-toluenesulfonamide; Tosyl Ethynyl Methyl Amine Derivative; Building Block 1005500-75-3
EINECS	Contact for details

Quality Control

Our n-Ethynyl-N,4-Dimethylbenzenesulfonamide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging during storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.