Description

2,4,6-Trifluorobenzamidine is a high-purity, fluorinated benzamidine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its unique trifluoromethyl-substituted aromatic ring, which imparts desirable properties like enhanced metabolic stability and lipophilicity to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of protease inhibitors, kinase inhibitors, and other small-molecule drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides with improved efficacy.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for designing activity-based probes and affinity ligands to study enzyme function.
• Material Science Precursor: Employed in the synthesis of fluorinated polymers, liquid crystals, and advanced organic materials.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for bespoke chemical synthesis services targeting specialized fluorinated compounds.

Basic Information

Product Name	2,4,6-Trifluorobenzamidine
CAS No.	1005460-15-0
Molecular Formula	C7H5F3N2
Molecular Weight	174.12 g/mol
Synonyms	2,4,6-Trifluorobenzenecarboximidamide; Benzenecarboximidamide, 2,4,6-trifluoro-; 2,4,6-Trifluorobenzene-1-carboximidamide; 2,4,6-Trifluorophenylformamidine; Trifluorobenzamidine
EINECS	Contact for details

Quality Control

Our 2,4,6-Trifluorobenzamidine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for research and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of GMP environments for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.