Description

2-(Triisopropylsilyl)-5-(Trimethylstannyl)Thiazole is a highly specialized organotin and organosilicon heterocyclic compound, serving as a critical building block in advanced synthetic chemistry. Its unique structure, combining a protected thiazole core with reactive tin and silicon functionalities, makes it an invaluable reagent for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries, particularly for applications in cross-coupling reactions and the development of novel electronic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing thiazole or complex heterocyclic systems.
• Stille Cross-Coupling Reactions: Serves as a versatile organotin reagent for forming carbon-carbon bonds, crucial for constructing complex molecules in medicinal chemistry and material science.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific heterocyclic frameworks.
• Materials Science & OLED Development: Employed in the synthesis of organic semiconductors, light-emitting diodes (OLEDs), and other advanced electronic materials due to its electron-rich thiazole core.
• Chemical Research & Process Development: A valuable tool for academic and industrial R&D labs exploring new synthetic methodologies and catalytic processes.
• Ligand and Catalyst Preparation: Can be utilized to develop novel ligands or organometallic catalysts for asymmetric synthesis and other catalytic transformations.

Basic Information

Product Name	2-(Triisopropylsilyl)-5-(Trimethylstannyl)Thiazole
CAS No.	1005196-16-6
Molecular Formula	C16H33NSSiSn
Molecular Weight	418.89 g/mol
Synonyms	5-(Trimethylstannyl)-2-(triisopropylsilyl)thiazole; 2-Triisopropylsilyl-5-trimethylstannylthiazole; Thiazole, 2-(triisopropylsilyl)-5-(trimethylstannyl)-; TIPS-Thiazole-SnMe3; (Triisopropylsilyl)(trimethylstannyl)thiazole
EINECS	Contact for details

Quality Control

Every batch of 2-(Triisopropylsilyl)-5-(Trimethylstannyl)Thiazole is manufactured and tested under strict quality management systems to ensure consistency and reliability for your critical applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring traceability and documentation for regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its moisture-sensitive and easily oxidized nature, the container must be kept tightly sealed and handled under inert conditions to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay (NMR)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.