Description

1-[8-(4-Bromophenyl)-6,7-Dimethyl-7,8-Dihydro-6H-[1,3]Dioxolo[4,5-G]Chromen-6-Yl]Pyrrolidine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in research targeting central nervous system and oncological pathways. It is essential for R&D chemists and process development scientists in pharmaceutical, biotechnology, and fine chemical industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of complex drug candidates, especially those with chromene and pyrrolidine pharmacophores.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new molecules with potential biological activity.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale under current Good Manufacturing Practices (cGMP).
• Chemical Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in API manufacturing.
• Academic & Institutional Research: Utilized in universities and research institutes for exploring new synthetic methodologies and heterocyclic chemistry.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and development services for the life sciences sector.

Basic Information

Product Name	1-[8-(4-Bromophenyl)-6,7-Dimethyl-7,8-Dihydro-6H-[1,3]Dioxolo[4,5-G]Chromen-6-Yl]Pyrrolidine
CAS No.	1005150-37-7
Molecular Formula	C24H24BrNO3
Molecular Weight	454.36 g/mol
Synonyms	1-[8-(4-Bromophenyl)-6,7-dimethyl-7,8-dihydro-6H-[1,3]dioxolo[4,5-g]chromen-6-yl]pyrrolidine; 6-(Pyrrolidin-1-yl)-8-(4-bromophenyl)-6,7-dimethyl-6,7-dihydro-5H-[1,3]dioxolo[4,5-g]chromene; 8-(4-Bromophenyl)-6,7-dimethyl-6-(pyrrolidin-1-yl)-6,7-dihydro-5H-[1,3]dioxolo[4,5-g]chromene; 1005150-37-7
EINECS	Contact for details

Quality Control

Our 1-[8-(4-Bromophenyl)-6,7-Dimethyl-7,8-Dihydro-6H-[1,3]Dioxolo[4,5-G]Chromen-6-Yl]Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect the compound from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.