Description

5-(1-Methyl-4-Nitro-1 H-Pyrazol-3-Yl)-Pyrazolo[1,5-A ]Pyrimidine-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially in oncology and antiviral research.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing libraries of novel compounds for high-throughput screening and structure-activity relationship (SAR) studies.
• API Process Development: Used in the scale-up and optimization of synthetic routes for new chemical entities (NCEs).
• Biochemical Reagent: May be employed in biochemical assays as a tool compound to study specific enzymatic or cellular pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	5-(1-Methyl-4-Nitro-1 H-Pyrazol-3-Yl)-Pyrazolo[1,5-A ]Pyrimidine-2-Carboxylic Acid
CAS No.	1004727-48-3
Molecular Formula	C12H8N6O5
Molecular Weight	316.23 g/mol
Synonyms	5-(1-Methyl-4-nitro-1H-pyrazol-3-yl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid; 5-(1-Methyl-4-nitro-pyrazol-3-yl)-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid; Pyrazolo[1,5-a]pyrimidine-2-carboxylic acid, 5-(1-methyl-4-nitro-1H-pyrazol-3-yl)-; UNII-7J3J4B6V1F; 7J3J4B6V1F; SCHEMBL21809027; AKOS040757623; DTXSID90672969
EINECS	Contact for details

Quality Control

Our production of 5-(1-Methyl-4-Nitro-1 H-Pyrazol-3-Yl)-Pyrazolo[1,5-A ]Pyrimidine-2-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized and released using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.