Description

3-Methyl-1-[(3S)-2-Oxooxolan-3-Yl]-3-{[2-(Propan-2-Yl)-1,3-Thiazol-4-Yl]Methyl}Urea is a sophisticated chiral urea derivative, a key building block in modern pharmaceutical research and development. This compound is valued for its unique molecular architecture, which incorporates a fused lactone (oxolanone) ring and an isopropyl-substituted thiazole moiety, enabling precise interactions in complex chemical syntheses. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new drug candidates, particularly in therapeutic areas targeting specific enzymes or receptors.
• Agrochemical Research: Serves as a building block for creating novel active ingredients with potential herbicidal, fungicidal, or insecticidal properties.
• Chemical Biology Probe: Used in academic and industrial research to study biological pathways and protein-ligand interactions due to its specific structural features.
• Process Chemistry Development: Employed in scaling up synthetic routes and optimizing manufacturing processes for complex molecules in pilot plants.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.
• Library Synthesis for High-Throughput Screening: Used to generate focused chemical libraries for screening against novel biological targets in drug discovery campaigns.

Basic Information

Product Name	3-Methyl-1-[(3S)-2-Oxooxolan-3-Yl]-3-{[2-(Propan-2-Yl)-1,3-Thiazol-4-Yl]Methyl}Urea
CAS No.	1004316-93-1
Molecular Formula	C14H19N3O3S
Molecular Weight	309.38 g/mol
Synonyms	3-Methyl-1-[(3S)-tetrahydro-2-oxo-3-furanyl]-3-[[2-(1-methylethyl)-4-thiazolyl]methyl]urea; (3S)-3-[[[[2-(1-Methylethyl)-4-thiazolyl]methyl]amino]carbonyl]amino]dihydro-2(3H)-furanone; Urea, N-[(3S)-2-oxo-3-oxolanyl]-N'-methyl-N'-[2-(1-methylethyl)-4-thiazolyl]methyl]-; CAS 1004316-93-1; Chiral Thiazole-Urea-Lactone Derivative
EINECS	Contact for details

Quality Control

Our 3-Methyl-1-[(3S)-2-Oxooxolan-3-Yl]-3-{[2-(Propan-2-Yl)-1,3-Thiazol-4-Yl]Methyl}Urea is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and isomeric purity suitable for demanding R&D applications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.