Description

tert-Butyl (6-Chloro-[1,2,4]Triazolo[4,3-B]Pyridazin-3-Yl)Methylcarbamate is a high-purity, advanced pharmaceutical intermediate characterized by its fused triazolopyridazine heterocyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily utilized by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of new chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, or oncology.
• Agrochemical Research: Used in the research and development of new generation herbicides or pesticides, leveraging its heterocyclic core for bioactivity.
• Chemical Biology & Proteomics: Employed as a specialized scaffold or linker in the design of chemical probes for studying enzyme function and protein interactions.
• Material Science Research: Investigated as a monomer or functional additive for creating polymers with specific electronic or photophysical properties.
• Academic & Industrial R&D: Utilized in methodological chemistry research for developing new synthetic routes involving chlorinated triazolopyridazine derivatives.

Basic Information

Product Name	tert-Butyl (6-Chloro-[1,2,4]Triazolo[4,3-B]Pyridazin-3-Yl)Methylcarbamate
CAS No.	1002310-30-6
Molecular Formula	C11H14ClN5O2
Molecular Weight	283.71 g/mol
Synonyms	tert-Butyl N-[(6-chloro-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl]carbamate; Carbamic acid, N-[(6-chloro[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl]-, 1,1-dimethylethyl ester; Boc-Protected 6-Chlorotriazolopyridazine Methylamine; 6-Chloro-3-(Boc-aminomethyl)-[1,2,4]triazolo[4,3-b]pyridazine; tert-Butyl ((6-chloro-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl)carbamate; 1002310-30-6; Boc-Aminomethyl-6-chlorotriazolopyridazine
EINECS	Contact for details

Quality Control

Our tert-Butyl (6-Chloro-[1,2,4]Triazolo[4,3-B]Pyridazin-3-Yl)Methylcarbamate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.