Description

Benzenemethanesulfonamide, 2-Chloro-4-Fluoro- is a high-purity, halogenated sulfonamide derivative serving as a critical synthetic intermediate. Its value lies in providing a functionalized aromatic scaffold for constructing more complex molecules in advanced research and development. This compound is primarily needed by pharmaceutical and agrochemical R&D teams for applications in medicinal chemistry and crop protection science.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and metabolic disorders.
• Agrochemical Research: Used in developing new generation herbicides and fungicides, leveraging the bioactivity of the chloro-fluoro substituted benzene ring.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialized polymers and advanced organic materials.
• Chemical Biology Probe: Utilized in biochemical research to create enzyme inhibitors or receptor ligands for pathway analysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes.

Basic Information

Product Name	Benzenemethanesulfonamide, 2-Chloro-4-Fluoro-
CAS No.	1001026-51-2
Molecular Formula	C7H7ClFNO2S
Molecular Weight	223.65 g/mol
Synonyms	2-Chloro-4-fluorobenzenemethanesulfonamide; α-Chloro-2-fluoro-4-methylbenzenesulfonamide; 1-(Chloromethyl)-2-fluoro-4-nitrobenzene sulfonamide; 2-Fluoro-4-chlorobenzenemethanesulfonamide; (2-Chloro-4-fluorophenyl)methanesulfonamide; 4-Fluoro-2-chlorobenzenemethanesulfonamide; Benzenemethanesulfonamide, 2-chloro-4-fluoro-; Toluene-2-chloro-4-fluoro-sulfonamide
EINECS	Contact for details

Quality Control

Every batch of Benzenemethanesulfonamide, 2-Chloro-4-Fluoro- is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed to verify identity, purity, and consistency. A Certificate of Analysis (COA) documenting all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.