Description

3,4-Dibromo-6-Fluoroiodobenzene is a high-purity, multi-halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique combination of bromine, fluorine, and iodine substituents makes it a versatile and valuable precursor for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as cross-coupling reactions and the development of novel active ingredients.

Application

This specialized halogenated benzene derivative serves as a critical intermediate in several high-value synthetic pathways.

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry for creating complex, halogenated aromatic cores.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorine and halogen atoms can enhance biological activity and stability.
• Material Science: A precursor for synthesizing advanced organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Cross-Coupling Reactions: The iodine and bromine atoms provide distinct sites for selective metal-catalyzed couplings (e.g., Suzuki, Stille, Negishi), enabling precise molecular assembly.
• Ligand Synthesis: Useful for creating custom ligands in catalysis and coordination chemistry.
• Chemical Research & Development: An essential reagent for exploring new synthetic methodologies and constructing complex, polyfunctionalized arenes in academic and industrial R&D settings.

Basic Information

Product Name	3,4-Dibromo-6-Fluoroiodobenzene
CAS No.	1000578-17-5
Molecular Formula	C6H2Br2FI
Molecular Weight	403.79 g/mol
Synonyms	1,2-Dibromo-4-fluoro-5-iodobenzene; 4-Fluoro-3,6-dibromo-1-iodobenzene; Benzene, 1,2-dibromo-4-fluoro-5-iodo-; 3,6-Dibromo-4-fluoroiodobenzene; 5-Iodo-3,4-dibromofluorobenzene
EINECS	Contact for details

Quality Control

Our 3,4-Dibromo-6-Fluoroiodobenzene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We employ advanced analytical techniques including HPLC, GC-MS, and NMR to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.