Description

2-Amino-5-Chloro-3-Iodobenzonitrile is a versatile halogenated benzonitrile derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring amino, chloro, and iodo substituents, makes it a valuable precursor for constructing complex molecules with tailored properties. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in heterocyclic chemistry for potential therapeutic agents.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its halogenated aromatic core.
• Material Science Precursor: Serves as a starting material for creating specialized dyes, pigments, and organic electronic materials.
• Cross-Coupling Reactions: The iodine and chlorine atoms make it an excellent substrate for Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions.
• Ligand and Complex Formation: The amino and nitrile groups allow for its use in designing novel ligands for catalysis or metal-organic frameworks (MOFs).
• Chemical Research & Development: A valuable reagent for academic and industrial R&D exploring new synthetic pathways and functional molecules.

Basic Information

Product Name	2-Amino-5-Chloro-3-Iodobenzonitrile
CAS No.	1000577-48-9
Molecular Formula	C7H4ClIN2
Molecular Weight	278.48 g/mol
Synonyms	5-Chloro-3-iodo-2-aminobenzonitrile; 2-Amino-5-chloro-3-iodobenzonitrile; Benzonitrile, 2-amino-5-chloro-3-iodo-; 3-Iodo-5-chloro-2-aminobenzonitrile; 2-Amino-3-iodo-5-chlorobenzonitrile; 5-Chloro-2-cyano-3-iodoaniline; 3-Iodo-5-chloroanthranilonitrile
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Chloro-3-Iodobenzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee it meets the stringent requirements for research and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.