Description

6-(Trifluoromethyl)-4-Oxo-4H-Pyran-2-Carboxylic Acid is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because its unique structure, featuring both a trifluoromethyl group and a pyranone-carboxylic acid moiety, enables the development of novel molecules with enhanced properties. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve biological activity and environmental stability.
• Material Science Precursor: Serves as a building block for functional polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing characteristics.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes and fluorescent tags for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	6-(Trifluoromethyl)-4-Oxo-4H-Pyran-2-Carboxylic Acid
CAS No.	1000350-06-0
Molecular Formula	C8H3F3O4
Molecular Weight	220.10 g/mol
Synonyms	4-Oxo-6-(trifluoromethyl)-4H-pyran-2-carboxylic acid; 6-(Trifluoromethyl)-4-oxo-4H-pyran-2-carboxylic acid; 2-Pyrancarboxylic acid, 6-(trifluoromethyl)-4-oxo-4H-; 4H-Pyran-2-carboxylic acid, 6-(trifluoromethyl)-4-oxo-; 1000350-06-0; 6-Trifluoromethyl-4-oxo-4H-pyran-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-(Trifluoromethyl)-4-Oxo-4H-Pyran-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if possible to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.