Description

3-Iodo-5-tert-Butylbenzoic Acid is a high-purity, halogenated benzoic acid derivative characterized by its unique sterically hindered tert-butyl group and iodine substituent. This compound serves as a versatile and valuable chemical intermediate in advanced organic synthesis, particularly for constructing complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting receptor modulation.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional polymers.
• Chemical Biology Probes: Useful for incorporating iodine labels or bulky aromatic groups into molecules for biochemical studies and probe development.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthetic routes and scale-up projects.

Basic Information

Product Name	3-Iodo-5-tert-Butylbenzoic Acid
CAS No.	1000341-29-6
Molecular Formula	C11H13IO2
Molecular Weight	304.13 g/mol
Synonyms	5-tert-Butyl-3-iodobenzoic Acid; 3-Iodo-5-(1,1-dimethylethyl)benzoic Acid; Benzoic acid, 3-iodo-5-(1,1-dimethylethyl)-; 3-Iodo-5-tert-butyl-benzoic acid; 1000341-29-6
EINECS	Contact for details

Quality Control

Every batch of 3-Iodo-5-tert-Butylbenzoic Acid is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.