Description

Ethyl 2-(6-Oxo-4-(Piperazin-1-Yl)Pyridazin-1(6H)-Yl)Acetate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a versatile pyridazinone-piperazine scaffold. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers targeting innovative therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Used in the multi-step production of potential active pharmaceutical ingredients targeting specific enzyme or receptor pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Biochemical Tool Compound: May be utilized in biochemical assays to study biological mechanisms and identify new therapeutic targets.

Basic Information

Product Name	Ethyl 2-(6-Oxo-4-(Piperazin-1-Yl)Pyridazin-1(6H)-Yl)Acetate
CAS No.	1000018-24-5
Molecular Formula	C12H18N4O3
Molecular Weight	266.30 g/mol
Synonyms	Ethyl 2-[4-(piperazin-1-yl)-6-oxopyridazin-1(6H)-yl]acetate; 1(6H)-Pyridazinone, 4-(1-piperazinyl)-, 1-acetic acid ethyl ester; 4-(Piperazin-1-yl)-1,6-dihydropyridazin-6-one 1-acetic acid ethyl ester; Ethyl [4-(piperazin-1-yl)-6-oxo-1,6-dihydropyridazin-1-yl]acetate; 1000018-24-5; UNII-7K3I4WY3Q5
EINECS	Contact for details

Quality Control

Our Ethyl 2-(6-Oxo-4-(Piperazin-1-Yl)Pyridazin-1(6H)-Yl)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.