Description

4-Nitro-2-(Trifluoromethyl)Phenylacetic Acid is a specialized fluorinated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a nitro and a trifluoromethyl group on the phenylacetic acid core, makes it a valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting enzymes or receptors where the trifluoromethyl group can enhance metabolic stability and binding affinity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the nitro and trifluoromethyl groups can contribute to biological activity and environmental persistence profiles.
• Material Science Precursor: Serves as a starting material for synthesizing advanced polymers, liquid crystals, or organic electronic materials that require fluorinated aromatic components.
• Chemical Synthesis Reagent: Employed in organic transformations, such as coupling reactions or as a precursor for further functionalization to create libraries of compounds for high-throughput screening.

Basic Information

Product Name	4-Nitro-2-(Trifluoromethyl)Phenylacetic Acid
CAS No.	199469-91-5
Molecular Formula	C9H6F3NO4
Molecular Weight	249.14 g/mol
Synonyms	2-(4-Nitro-2-(trifluoromethyl)phenyl)acetic acid; [4-Nitro-2-(trifluoromethyl)phenyl]acetic Acid; α-(4-Nitro-2-trifluoromethylphenyl)acetic Acid; 4-Nitro-α,α,α-trifluoro-o-toluic Acid (related); 2-(Trifluoromethyl)-4-nitrophenylacetic Acid; 199469-91-5; (4-Nitro-2-trifluoromethylphenyl)acetic acid
EINECS	Contact for details

Quality Control

Every batch of 4-Nitro-2-(Trifluoromethyl)Phenylacetic Acid is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specified parameters is provided with each shipment to guarantee it meets your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.