Description

4-Aminotetrahydropyran-4-Carboxylic Acid Methyl Ester Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its unique tetrahydropyran scaffold. This compound is of significant commercial importance for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought after by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• API Synthesis: Used in the construction of complex active pharmaceutical ingredients (APIs) that incorporate the tetrahydropyran moiety for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, and insecticides with improved efficacy.
• Chemical Biology & Medicinal Chemistry: Employed in research for probing biological pathways and as a scaffold in combinatorial chemistry libraries for drug discovery.
• Fine Chemical Production: Utilized in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring specific chiral or structural elements.

Basic Information

Product Name	4-Aminotetrahydropyran-4-Carboxylic Acid Methyl Ester Hydrochloride
CAS No.	199330-66-0
Molecular Formula	C8H16ClNO3
Molecular Weight	209.67 g/mol
Synonyms	Methyl 4-aminotetrahydropyran-4-carboxylate hydrochloride; 4-Aminooxane-4-carboxylic acid methyl ester hydrochloride; 4-Amino-THP-4-carboxylic acid methyl ester HCl; 4-Aminotetrahydropyran-4-carboxylic acid methyl ester HCl salt; Methyl 4-aminooxane-4-carboxylate hydrochloride; 4-Amino-4-methoxycarbonyltetrahydropyran hydrochloride; 4-(Methoxycarbonyl)-4-aminotetrahydropyran hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Aminotetrahydropyran-4-Carboxylic Acid Methyl Ester Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.