Description

Methyl 3-Amino-3-(4-Methylphenyl)Propanoate is a versatile chiral β-amino acid ester derivative, serving as a critical building block in modern organic synthesis. Its value lies in its bifunctional structure, featuring both an amino group and an ester moiety, which enables its use in constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs), peptidomimetics, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, including potential enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its structural motif for bioactivity.
• Peptidomimetics & Bioactive Molecules: Serves as a non-natural amino acid derivative for creating peptide analogs with enhanced metabolic stability and potency.
• Asymmetric Catalysis & Ligand Development: Employed as a precursor for chiral ligands and catalysts used in stereoselective transformations.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry programs.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals and advanced materials.

Basic Information

Product Name	Methyl 3-Amino-3-(4-Methylphenyl)Propanoate
CAS No.	198959-38-5
Molecular Formula	C11H15NO2
Molecular Weight	193.24 g/mol
Synonyms	Methyl 3-amino-3-(p-tolyl)propanoate; β-Amino-4-methylbenzenepropanoic acid methyl ester; 3-Amino-3-(4-methylphenyl)propionic acid methyl ester; Methyl β-amino-β-(4-methylphenyl)propionate; (R/S)-Methyl 3-amino-3-(4-methylphenyl)propanoate; 198959-38-5; Benzenepropanoic acid, β-amino-4-methyl-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Amino-3-(4-Methylphenyl)Propanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.