Description

Benzenesulfonamide, 4-(((6-Chloro-5-Methyl-4-Oxo-4H-1-Benzopyran-3-Yl) Methylene)Amino)-n-((Phenylamino)Thioxomethyl)- is a specialized organic compound featuring a complex molecular architecture that combines chromone and sulfonamide pharmacophores. This structure makes it a valuable advanced intermediate for research and development in medicinal chemistry, particularly for targeting specific biological pathways. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in synthesizing novel active pharmaceutical ingredients (APIs) and biochemical probes.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting enzymes or receptors where the chromone and sulfonamide motifs are relevant.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of lead compounds.
• Biochemical Probe Development: Serves as a precursor for creating labeled or modified compounds used to study biological mechanisms and identify new therapeutic targets.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses to produce complex, high-value molecules for academic and industrial research.
• Reference Standard: Supplied as a high-purity compound for analytical method development, validation, and quality control in API manufacturing.

Basic Information

Product Name	Benzenesulfonamide, 4-(((6-Chloro-5-Methyl-4-Oxo-4H-1-Benzopyran-3-Yl) Methylene)Amino)-n-((Phenylamino)Thioxomethyl)-
CAS No.	198649-77-3
Molecular Formula	C24H18ClN3O4S2
Molecular Weight	512.00 g/mol
Synonyms	4-[(E)-[(6-Chloro-5-methyl-4-oxo-4H-chromen-3-yl)methylidene]amino]-N-(phenylcarbamothioyl)benzenesulfonamide; N-[(6-Chloro-5-methyl-4-oxo-4H-chromen-3-yl)methylidene]-4-[(phenylcarbamothioyl)amino]benzenesulfonamide; 4-(((6-Chloro-5-methyl-4-oxo-4H-chromen-3-yl)methylene)amino)-N-((phenylamino)thioxomethyl)benzenesulfonamide; Chromone-sulfonamide derivative; CAS 198649-77-3
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Each batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliant manufacturing for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.