Description

Fmoc-L-Lysinol(Boc) CAS NO 198561-38-5 is a protected amino alcohol derivative, specifically designed as a critical building block in solid-phase peptide synthesis (SPPS). Its primary value lies in enabling the controlled introduction of lysine side-chain modifications, which are essential for creating peptides with enhanced stability, solubility, and biological activity. This high-purity intermediate is indispensable for researchers and manufacturers in pharmaceutical development, biotechnology, and advanced materials science who require precise molecular control.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the site-specific incorporation of orthogonally protected lysine residues.
• Pharmaceutical Research: Used in the development of peptide-based therapeutics, including hormone analogs, antimicrobial peptides, and targeted drug conjugates.
• Bioconjugation: Serves as a linker or spacer molecule for attaching functional groups, labels (e.g., fluorophores), or other molecules to peptides or proteins.
• Material Science: A precursor for synthesizing peptide amphiphiles and other bio-inspired polymers for nanotechnology and drug delivery systems.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to discover new bioactive compounds.
• Antibody-Drug Conjugate (ADC) Development: Facilitates the construction of stable, cleavable linkers between cytotoxic payloads and antibodies.

Basic Information

Product Name	Fmoc-L-Lysinol(Boc)
CAS No.	198561-38-5
Molecular Formula	C26H34N2O5
Molecular Weight	454.56 g/mol
Synonyms	Fmoc-Lys(Boc)-ol; Nα-Fmoc-Nε-Boc-L-lysinol; (2S)-6-{[(2-Methylpropan-2-yl)oxy]carbonylamino}-2-(9H-fluoren-9-ylmethoxycarbonylamino)hexan-1-ol; Fmoc-Lys(Boc)-OH-ol; Boc-Lys(Fmoc)-ol; Fmoc-L-Lys(Boc)-ol; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N'-[(1,1-dimethylethoxy)carbonyl]-L-lysine alcohol
EINECS	Contact for details

Quality Control

Our Fmoc-L-Lysinol(Boc) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and chiral integrity, meeting the exacting standards required for peptide synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.