Description

L-Glutamine, N2-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-n-Phenyl- is a protected glutamine derivative, specifically an Fmoc-protected amino acid building block. This compound is critical for ensuring high-purity peptide synthesis by protecting the reactive amine group during solid-phase and solution-phase coupling reactions. It is an essential raw material for research institutions and manufacturers in the pharmaceutical, biotechnology, and peptide synthesis sectors.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the automated synthesis of complex peptides and proteins.
• Solution-Phase Peptide Synthesis: Used in classical peptide bond formation strategies requiring selective deprotection.
• Pharmaceutical Intermediate: Serves as a crucial building block in the research and development of peptide-based therapeutics and APIs.
• Bioconjugation and Labeling: Enables the site-specific incorporation of glutamine residues for creating labeled probes or antibody-drug conjugates.
• Combinatorial Chemistry: Used in libraries for drug discovery to generate diverse peptide structures.
• Biochemical Research: A reagent for studying enzyme mechanisms, protein-protein interactions, and metabolic pathways involving glutamine.

Basic Information

Product Name	L-Glutamine, N2-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-n-Phenyl-
CAS No.	198134-12-2
Molecular Formula	C26H24N2O5
Molecular Weight	444.48 g/mol
Synonyms	Fmoc-Gln-Ph; Fmoc-L-glutamine N-phenylamide; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-glutamine N'-phenylamide; N2-Fmoc-N-phenyl-L-glutamine; Nα-Fmoc-N'-phenyl-L-glutamine; Fmoc-L-Gln(NH-Ph)-OH; (2S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-5-(phenylamino)-5-oxopentanoic acid
EINECS	Contact for details

Quality Control

Our Fmoc-protected amino acids are manufactured under strict quality systems to ensure batch-to-batch consistency for sensitive synthesis workflows. Each lot undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm enantiomeric integrity. A Certificate of Analysis (COA) detailing specifications for identity, assay, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.