Description

D-Glutamic Acid, n-Hydroxy- (9Ci) CAS NO 197861-16-8 is a specialized, non-proteinogenic amino acid derivative of glutamic acid, featuring a hydroxyl group substitution on the nitrogen atom. This unique structural modification makes it a valuable chiral building block and intermediate in advanced organic synthesis and pharmaceutical research. It is particularly sought after by research scientists and process chemists in the pharmaceutical, agrochemical, and fine chemical industries for developing novel active compounds and studying biochemical pathways.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for neurological and metabolic targets.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate the function of glutamate-related enzymes and receptors.
• Peptide Synthesis: Employed as a modified amino acid residue in the synthesis of specialized peptides with enhanced stability or novel biological activity.
• Agrochemical Development: Acts as a precursor in the design and synthesis of new herbicides, pesticides, or plant growth regulators.
• Fine Chemical Synthesis: Utilized as a high-value building block for creating complex molecules in asymmetric synthesis and catalysis research.
• Reference Standard: Provides a high-purity standard for analytical method development and quality control in related chemical production.

Basic Information

Item	Details
Product Name	D-Glutamic Acid, n-Hydroxy- (9Ci)
CAS No.	197861-16-8
Molecular Formula	C5H9NO5
Molecular Weight	163.13 g/mol
Synonyms	N-Hydroxy-D-glutamic Acid; (R)-2-Amino-4-hydroxy-4-oxobutanoic Acid N-Oxide; D-2-Amino-4-hydroxy-4-oxobutanoic Acid Hydroxamate; H-D-Glu(N-OH)-OH; N-Hydroxy-D-glutamate; Hydroxyamino-D-glutamic Acid; D-Isomer of N-Hydroxyglutamic Acid
EINECS	Contact for details

Quality Control

Our D-Glutamic Acid, n-Hydroxy- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every lot to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere to minimize oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (D-Isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.