Description

3-Chloro-2-[3-(Trifluoromethyl)Phenoxy]Pyridine is a high-value, multi-functional heterocyclic building block characterized by its unique combination of a pyridine core, a chloro substituent, and a trifluoromethylphenoxy group. This molecular architecture makes it a critical intermediate for the synthesis of advanced agrochemicals and pharmaceuticals, where it imparts desirable properties such as enhanced biological activity and metabolic stability. It is primarily sought after by R&D chemists and process development scientists in the agrochemical and pharmaceutical industries for creating novel active ingredients and fine chemicals.

Application

• Agrochemical Intermediate: A key synthon for the development of next-generation herbicides, insecticides, and fungicides, leveraging the bioactivity of the pyridine and trifluoromethyl motifs.
• Pharmaceutical Building Block: Used in medicinal chemistry for the synthesis of drug candidates targeting various disease pathways, where the chloro and trifluoromethyl groups are essential for potency and ADME optimization.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in catalysis and material science applications.
• Organic Synthesis Research: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and exploring novel chemical reactions.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals used in electronics and advanced materials.

Basic Information

Product Name	3-Chloro-2-[3-(Trifluoromethyl)Phenoxy]Pyridine
CAS No.	197565-66-5
Molecular Formula	C12H7ClF3NO
Molecular Weight	273.64 g/mol
Synonyms	2-(3-Chloropyridin-2-yloxy)-α,α,α-trifluorotoluene; 3-Chloro-2-(3-trifluoromethylphenoxy)pyridine; 2-(3-Trifluoromethylphenoxy)-3-chloropyridine; 3-Chloro-2-(α,α,α-trifluoro-m-tolyloxy)pyridine; m-Trifluoromethylphenyl 3-chloro-2-pyridyl ether; 3-Chloro-2-(3-(trifluoromethyl)phenoxy)pyridine
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for this advanced intermediate. Every batch is analyzed using modern analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. Our quality system is designed to support cGMP requirements for pharmaceutical development and meets the high standards demanded by agrochemical innovators.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.