Description

4-Piperazin-1-Yl-Pyridazine is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs). Pharmaceutical R&D and fine chemical synthesis companies need it to create novel compounds for drug discovery programs targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides that require specific heterocyclic motifs for bioactivity.
• Ligand & Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic semiconductors, photoactive materials, and advanced polymers.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical building block supplied to CDMOs for the production of bespoke compounds under cGMP conditions.

Basic Information

Product Name	4-Piperazin-1-Yl-Pyridazine
CAS No.	194853-84-4
Molecular Formula	C8H12N4
Molecular Weight	164.21 g/mol
Synonyms	4-(Piperazin-1-yl)pyridazine; 1-(Pyridazin-4-yl)piperazine; 4-Piperazin-1-ylpyridazine; Pyridazine, 4-(1-piperazinyl)-; 4-Piperazinylpyridazine; 194853-84-4; 4-(1-Piperazinyl)pyridazine
EINECS	Contact for details

Quality Control

Our 4-Piperazin-1-Yl-Pyridazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development and commercial projects requiring compliance with ICH guidelines and can supply material suitable for use under cGMP conditions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.