Description

3-Methyl-6,7,8,9-Tetrahydro-5Ah-Pyrano[4,3-B]Chromen-1-One is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyranochromenone class of heterocyclic compounds. This compound is valued for its complex molecular architecture, which serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, especially for central nervous system (CNS) and anti-inflammatory targets.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes from laboratory to pilot and commercial production.
• Organic Synthesis Building Block: Employed in the construction of complex fused heterocyclic systems due to its pyranochromenone framework.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis projects requiring high-purity, specialized intermediates.
• Academic Research: Utilized in university and institutional labs for studies in organic synthesis methodology and heterocyclic chemistry.

Basic Information

Product Name	3-Methyl-6,7,8,9-Tetrahydro-5Ah-Pyrano[4,3-B]Chromen-1-One
CAS No.	194796-93-5
Molecular Formula	C15H16O3
Molecular Weight	244.29 g/mol
Synonyms	3-Methyl-6,7,8,9-tetrahydro-5aH-pyrano[4,3-b]chromen-1-one; 5aH-Pyrano[4,3-b]chromen-1-one, 6,7,8,9-tetrahydro-3-methyl-; 3-Methyl-6,7,8,9-tetrahydro-5aH-pyrano[4,3-b]chromen-1-one; Fused Pyranochromenone Derivative; Chromenopyranone Intermediate
EINECS	Contact for details

Quality Control

Our production of 3-Methyl-6,7,8,9-Tetrahydro-5Ah-Pyrano[4,3-B]Chromen-1-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for pharmaceutical research. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. Our quality system is designed to support regulatory filings and GMP-grade requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.