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Ethyl 2-Amino-4-(4-Chlorophenyl)-6-(Hydroxymethyl)-8-Oxo-4,8-Dihydropyrano[3,2-B]Pyran-3-Carboxylate CAS NO 194282-66-1


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CAS No.:194282-66-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Ethyl 2-Amino-4-(4-Chlorophenyl)-6-(Hydroxymethyl)-8-Oxo-4,8-Dihydropyrano[3,2-B]Pyran-3-Carboxylate is a high-purity, synthetically derived heterocyclic compound that serves as a critical advanced intermediate in modern organic synthesis. Its complex fused pyranopyran structure, featuring amino, hydroxymethyl, and ester functionalities, makes it a versatile building block for constructing pharmacologically active molecules. This compound is primarily sought by research institutions and pharmaceutical development companies engaged in the discovery and synthesis of novel therapeutic agents.

Application

  • Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in therapeutic areas targeting inflammation, metabolic disorders, or infectious diseases.
  • Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
  • Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes to study biological pathways and enzyme functions.
  • Organic Synthesis Building Block: Utilized in multi-step synthetic routes to create complex natural product analogs or other fused heterocyclic systems.
  • Agrochemical Intermediate: Potential application in the research and development of new active ingredients for crop protection.
  • Academic & Institutional Research: Used in universities and R&D centers for methodological studies in heterocyclic and multi-component reaction chemistry.

Basic Information

Product Name Ethyl 2-Amino-4-(4-Chlorophenyl)-6-(Hydroxymethyl)-8-Oxo-4,8-Dihydropyrano[3,2-B]Pyran-3-Carboxylate
CAS No. 194282-66-1
Molecular Formula C18H16ClNO6
Molecular Weight 377.78 g/mol
Synonyms Ethyl 2-Amino-4-(4-chlorophenyl)-6-(hydroxymethyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carboxylate; 4H,8H-Pyrano[3,2-b]pyran-3-carboxylic acid, 2-amino-4-(4-chlorophenyl)-6-(hydroxymethyl)-8-oxo-, ethyl ester; 194282-66-1; Ethyl 2-amino-4-(p-chlorophenyl)-6-(hydroxymethyl)-8-oxo-4,8-dihydropyrano[3,2-b]pyran-3-carboxylate; Pyrano[3,2-b]pyran derivative CAS 194282-66-1
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Quality Control

Our Ethyl 2-Amino-4-(4-Chlorophenyl)-6-(Hydroxymethyl)-8-Oxo-4,8-Dihydropyrano[3,2-B]Pyran-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed when not in use to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 97.0%
Single Unknown Impurity (HPLC) ≤ 1.0%
Total Impurities (HPLC) ≤ 3.0%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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