Description

3-Pyridazinemethanol,5-Fluorohexahydro-4-Hydroxy-,(3Alpha,4Beta,5Alpha)-(9Ci) is a high-purity, stereochemically defined fluorinated pyridazine derivative. This compound serves as a critical advanced pharmaceutical intermediate for the synthesis of novel active ingredients, particularly in therapeutic areas requiring precise molecular architecture. It is primarily utilized by research institutions and pharmaceutical R&D departments engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates targeting central nervous system (CNS) disorders, metabolic diseases, and anti-infective agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore the impact of fluorination and hydroxylation on bioactivity and metabolic stability.
• Process Development: Serves as a reference standard and starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Agrochemical Research: Potential intermediate in the development of novel, fluorinated pesticides and herbicides with enhanced efficacy.
• Chemical Biology Probe: Utilized in biochemical assays to study enzyme inhibition or receptor binding mechanisms due to its specific stereochemistry.

Basic Information

Product Name	3-Pyridazinemethanol,5-Fluorohexahydro-4-Hydroxy-,(3Alpha,4Beta,5Alpha)-(9Ci)
CAS No.	194040-35-2
Molecular Formula	C6H11FN2O2
Molecular Weight	162.16 g/mol
Synonyms	(3α,4β,5α)-5-Fluorohexahydro-4-hydroxy-3-pyridazinemethanol; 5-Fluorohexahydro-4-hydroxy-3-pyridazinemethanol (3α,4β,5α)-isomer; 3-Pyridazinemethanol, 5-fluorohexahydro-4-hydroxy-, (3α,4β,5α)-; (3R,4S,5R)-5-Fluoro-4-hydroxypiperidine-3-methanol; 194040-35-2; Fluorinated pyridazine alcohol intermediate; Stereoisomeric fluoropyridazine derivative.
EINECS	Contact for details

Quality Control

Every batch of this high-purity intermediate is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to support your regulatory filings, including HPLC purity, chiral purity, and identity confirmation. Certificates of Analysis (COA) detailing lot-specific results are available upon request and can be tailored to meet GMP or research-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.