Description

1,3-Bis[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]-5-Ethenylbenzene is a high-purity, protected phenolic intermediate featuring tert-butyldimethylsilyl (TBDMS) ether groups and a reactive vinyl substituent. This compound is critical for advanced organic synthesis, offering a versatile building block for constructing complex molecular architectures where selective deprotection and further functionalization are required. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries for the synthesis of active pharmaceutical ingredients (APIs), ligands, and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key protected precursor in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of advanced pesticides, herbicides, and plant growth regulators.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing sophisticated ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer & Material Science: The vinyl group enables incorporation into polymers via polymerization or grafting, useful for creating specialty resins and functionalized surfaces.
• Organic Synthesis Building Block: Provides a versatile platform for further chemical transformations, including cross-coupling reactions, oxidation, and cycloadditions, after selective deprotection of the silyl groups.
• Academic & Industrial R&D: Essential for methodological development and exploring new synthetic pathways in research laboratories.

Basic Information

Product Name	1,3-Bis[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]-5-Ethenylbenzene
CAS No.	193695-64-6
Molecular Formula	C20H36O2Si2
Molecular Weight	364.68 g/mol
Synonyms	5-Vinyl-1,3-phenylene bis(tert-butyldimethylsilyl) ether; 1,3-Bis[(tert-butyldimethylsilyl)oxy]-5-vinylbenzene; 5-Ethenyl-1,3-phenylene bis[(1,1-dimethylethyl)dimethylsilyl] ether; 3,5-Bis-O-(tert-butyldimethylsilyl)vinylbenzene; TBDMS-protected 3,5-dihydroxyvinylbenzene; 1,3-Bis-O-TBDMS-5-vinylbenzene; 193695-64-6; 5-Vinylresorcinol bis(TBDMS) ether
EINECS	Contact for details

Quality Control

Our 1,3-Bis[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]-5-Ethenylbenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the stringent requirements for research and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.