Description

3-Ethoxy-3-Oxopropylzinc Bromide is a highly reactive organozinc reagent, specifically a Reformatsky-type reagent, used for the efficient formation of carbon-carbon bonds. This compound matters for its role as a key synthetic intermediate in the production of complex organic molecules, particularly β-keto esters and other fine chemicals. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for advanced organic synthesis and process development.

Application

• Key intermediate in the synthesis of pharmaceutical active ingredients (APIs) and drug candidates.
• Building block for the production of complex β-keto esters and other fine chemicals.
• Reagent for Reformatsky-type reactions in advanced organic synthesis.
• Used in cross-coupling reactions to introduce functionalized alkyl chains.
• Research and development tool in medicinal chemistry for creating novel molecular scaffolds.
• Precursor in the synthesis of specialized ligands and materials for agrochemicals.

Basic Information

Product Name	3-Ethoxy-3-Oxopropylzinc Bromide
CAS No.	193065-68-8
Molecular Formula	C5H9BrO2Zn
Molecular Weight	246.42 g/mol
Synonyms	Ethyl 3-(Bromozincio)propanoate; Zinc, bromo(3-ethoxy-3-oxopropyl)-; 3-Ethoxy-3-oxopropylzinc bromide solution; Reformatsky Reagent (Ethyl bromozincacetate); Bromo(3-ethoxy-3-oxopropyl)zinc; Ethyl 2-(bromozincio)acetate homologue; Propanoic acid, 3-(bromozincio)-, ethyl ester
EINECS	Contact for details

Quality Control

Our 3-Ethoxy-3-Oxopropylzinc Bromide is produced under stringent conditions to ensure high reactivity and consistency. Each batch undergoes rigorous quality testing, including assay and impurity profiling, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, concentration (typically supplied as a solution in THF or other solvents), and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Due to its properties as a highly volatile and easily oxidized compound, it must be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C for solutions. Handle and store away from moisture, strong acids, and oxidizing agents in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (IR)	Conforms to structure
Assay (Zinc content)	Contact for details
Concentration (Typical)	0.5 M in THF (or as specified)
Purity (GC/HPLC)	≥ 95% (or as per grade)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.