Description

tert-Butyl(4R, 6R)-2-[6-(2-Aminoethyl)-2,2-Dimethyl-1,3-Dioxan-4-Yl]Acetate is a high-purity chiral intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a key building block for the production of complex, biologically active molecules, particularly in pharmaceutical research and development. This compound is essential for chemists and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require a reliable and high-quality source for sophisticated synthetic pathways.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for cardiovascular and cholesterol-lowering drugs.
• Asymmetric Synthesis: Used as a key starting material or intermediate in stereoselective reactions to construct complex molecular architectures.
• Agrochemical Research: Serves as a building block for developing novel, optically active pesticides and herbicides.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & R&D Laboratories: Utilized in research for method development and the discovery of new synthetic routes to bioactive compounds.
• Process Chemistry Development: Acts as a reference standard and intermediate for scaling up synthetic processes from lab to pilot plant and commercial production.

Basic Information

Product Name	tert-Butyl(4R, 6R)-2-[6-(2-Aminoethyl)-2,2-Dimethyl-1,3-Dioxan-4-Yl]Acetate
CAS No.	191917-91-6
Molecular Formula	C15H27NO4
Molecular Weight	285.38 g/mol
Synonyms	(4R,6R)-6-(2-Aminoethyl)-2,2-dimethyl-1,3-dioxan-4-ylacetic acid tert-butyl ester; tert-Butyl (4R,6R)-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate; (4R-cis)-6-[2-(Aminoethyl)]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester; (4R,6R)-6-(2-Aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester; Atorvastatin tert-butyl ester intermediate; tert-Butyl (4R,6R)-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxan-4-ylacetate
EINECS	Contact for details

Quality Control

Our tert-Butyl(4R, 6R)-2-[6-(2-Aminoethyl)-2,2-Dimethyl-1,3-Dioxan-4-Yl]Acetate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including chiral HPLC, to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.