Description

7-(Trifluoromethyl)Chroman-4-Amine Hydrochloride is a high-purity, fluorinated organic building block of significant interest in advanced chemical synthesis. This compound is valued for its role in introducing the trifluoromethyl group and chroman scaffold into target molecules, which can dramatically alter their physicochemical and biological properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the design and production of novel pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Chemical Research: Serves as a versatile building block in medicinal chemistry and organic synthesis for constructing complex heterocyclic compounds.
• Material Science: Potential precursor in the development of advanced organic materials, such as liquid crystals or functional polymers.

Basic Information

Product Name	7-(Trifluoromethyl)Chroman-4-Amine Hydrochloride
CAS No.	191608-40-9
Molecular Formula	C10H11ClF3NO
Molecular Weight	253.65 g/mol
Synonyms	4-Amino-7-(trifluoromethyl)chroman hydrochloride; 7-(Trifluoromethyl)-3,4-dihydro-2H-1-benzopyran-4-amine hydrochloride; 4-Amino-7-trifluoromethylchroman HCl; 7-Trifluoromethylchroman-4-amine HCl; 191608-40-9; Chroman-4-amine, 7-(trifluoromethyl)-, hydrochloride
EINECS	Contact for details

Quality Control

Our 7-(Trifluoromethyl)Chroman-4-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.