Description

8-Chloro-Chroman-4-Ylamine Hydrochloride is a high-purity, synthetically derived organic compound primarily used as a key chiral intermediate in advanced pharmaceutical synthesis. Its value lies in its specific molecular architecture, which is crucial for constructing complex molecules with defined stereochemistry. This compound is essential for research and development chemists and process scale-up teams in the pharmaceutical and fine chemical industries, particularly for creating active pharmaceutical ingredients (APIs) and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Organic Synthesis Research: Used in academic and industrial R&D for exploring new synthetic pathways and methodologies.
• Asymmetric Catalysis Studies: Serves as a substrate or ligand precursor in the development of stereoselective catalytic reactions.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals.
• Reference Standard: Utilized as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	8-Chloro-Chroman-4-Ylamine Hydrochloride
CAS No.	191608-19-2
Molecular Formula	C9H11Cl2NO
Molecular Weight	220.10 g/mol
Synonyms	8-Chloro-3,4-dihydro-2H-1-benzopyran-4-amine hydrochloride; 4-Amino-8-chlorochroman hydrochloride; 8-Chloro-4-chromanamine hydrochloride; (4-Amino-8-chloro-3,4-dihydro-2H-chromen) hydrochloride; 191608-19-2; 8-Chloro-3,4-dihydro-2H-chromen-4-amine HCl; 8-Chloro-4-aminochroman hydrochloride
EINECS	Contact for details

Quality Control

Our 8-Chloro-Chroman-4-Ylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.