Description

1-Methyl-5-(Tributylstannyl)-3-(Trifluoromethyl)-1H-Pyrazole is a specialized organotin reagent featuring a pyrazole core functionalized with a trifluoromethyl group. This compound is a critical building block in modern synthetic chemistry, enabling the efficient introduction of complex heterocyclic motifs into target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated pyrazole scaffolds for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethylpyrazole unit contributes to improved efficacy and environmental profile.
• Cross-Coupling Reactions: Serves as a versatile organotin reagent in Stille cross-coupling reactions to form carbon-carbon bonds, facilitating the construction of complex molecular architectures.
• Material Science Research: Employed in the development of novel organic electronic materials and metal-organic frameworks (MOFs) due to its unique electronic properties and coordination ability.
• Ligand Synthesis: Acts as a precursor for creating specialized ligands used in catalysis and metal complexation studies.

Basic Information

Product Name	1-Methyl-5-(Tributylstannyl)-3-(Trifluoromethyl)-1H-Pyrazole
CAS No.	191606-78-7
Molecular Formula	C17H31F3N2Sn
Molecular Weight	439.14 g/mol
Synonyms	5-(Tributylstannyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazole; 1-Methyl-3-trifluoromethyl-5-tributylstannylpyrazole; Tributyl(1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)stannane; 1-Methyl-5-tributylstannyl-3-trifluoromethylpyrazole; 1H-Pyrazole, 1-methyl-5-(tributylstannyl)-3-(trifluoromethyl)-; Stannane, tributyl[1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl]-
EINECS	Contact for details

Quality Control

Our 1-Methyl-5-(Tributylstannyl)-3-(Trifluoromethyl)-1H-Pyrazole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is analyzed using advanced techniques including NMR (1H, 13C, 19F) and HPLC to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Keep away from heat and incompatible materials. Due to its sensitivity, the container should be kept sealed and only opened in a controlled environment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Tin (Sn) Content	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.