Description

Bicyclo[3.1.0]Hexane-2,6-Dicarboxylic Acid, 2-Amino-3-Methyl- is a high-purity, multifunctional bicyclic amino acid derivative of significant interest in advanced organic synthesis. This compound matters for its unique constrained molecular framework, which serves as a sophisticated building block for creating novel molecular architectures with specific stereochemical and conformational properties. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, chiral catalyst development, and the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• Agrochemical Synthesis: Used in the design and synthesis of novel herbicides, fungicides, and insecticides, leveraging its rigid structure for enhanced biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to produce enantiomerically pure compounds.
• Peptidomimetics and Conformationally Restricted Peptides: The bicyclic scaffold is incorporated to mimic peptide secondary structures, aiding in drug discovery for metabolic diseases and oncology.
• Material Science Research: Investigated as a monomer or additive for creating polymers with unique thermal and mechanical properties.
• Academic and R&D Laboratories: Employed as a reference standard and a versatile starting material for methodological studies in organic chemistry.

Basic Information

Product Name	Bicyclo[3.1.0]Hexane-2,6-Dicarboxylic Acid, 2-Amino-3-Methyl-
CAS No.	191342-39-9
Molecular Formula	C10H13NO4
Molecular Weight	211.21 g/mol
Synonyms	2-Amino-3-methylbicyclo[3.1.0]hexane-2,6-dicarboxylic acid; 3-Methyl-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid; (1R,5S,6R)-2-Amino-3-methylbicyclo[3.1.0]hexane-2,6-dicarboxylic acid (stereoisomer); 2-Aza-3-methylbicyclo[3.1.0]hexane-2,6-dicarboxylic acid derivative; Constrained glutamic acid analog; Bicyclo[3.1.0]hexane amino diacid
EINECS	Contact for details

Quality Control

Our Bicyclo[3.1.0]Hexane-2,6-Dicarboxylic Acid, 2-Amino-3-Methyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure compliance with exacting research and process chemistry standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.