Description

(S,S'')-2,2''-Bis[(S)-4-Isopropyloxazolin-2-Yl]-1,1''-Biferrocene is a sophisticated chiral ligand and organometallic complex, renowned for its unique structural framework combining ferrocene and oxazoline motifs. This compound is highly valued for its exceptional ability to induce stereoselectivity in asymmetric catalysis, a critical requirement for producing enantiomerically pure intermediates in advanced synthesis. It is an essential tool for research chemists and process developers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop efficient and selective synthetic routes.

Application

• Asymmetric Catalysis: Serves as a highly effective chiral ligand for transition metal-catalyzed reactions, including hydrogenation, hydrosilylation, and cross-coupling.
• Pharmaceutical Intermediate Synthesis: Critical for the enantioselective construction of complex molecules, enabling the production of single-isomer active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of chiral pesticides and herbicides where specific stereochemistry is required for biological activity.
• Material Science: Investigated for creating chiral molecular materials and sensors due to its redox-active ferrocene units and defined chirality.
• Academic & Process Chemistry: A valuable reference compound and reagent for methodological development in asymmetric synthesis and mechanistic studies.

Basic Information

Product Name	(S,S'')-2,2''-Bis[(S)-4-Isopropyloxazolin-2-Yl]-1,1''-Biferrocene
CAS No.	190601-12-8
Molecular Formula	C34H38Fe2N2O2
Molecular Weight	618.37 g/mol
Synonyms	(S,S)-2,2'-Bis[(S)-4-Isopropyl-2-oxazolinyl]-1,1'-biferrocene; (S,S)-BIFOX; (S,S)-Biferrocenyl-bis(oxazoline); (S,S)-BIFOX Ligand; (S,S)-2,2'-Bis[(S)-4-(1-Methylethyl)-4,5-dihydro-2-oxazolyl]-1,1'-biferrocene; (S,S)-BIFOX-Fc; Biferrocene-based bis(oxazoline) ligand; CAS 190601-12-8
EINECS	Contact for details

Quality Control

Every batch of our (S,S'')-2,2''-Bis[(S)-4-Isopropyloxazolin-2-Yl]-1,1''-Biferrocene is synthesized and purified under stringent conditions to ensure high chiral purity and chemical integrity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing chiral purity (by HPLC), assay, and identity confirmation are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to prevent oxidation and degradation. Keep the container in a cool, dry, and well-ventilated place.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.