Description

2H-Pyran-2-Methanol,6-Ethoxytetrahydro-3-Methyl-,Acetate,(2S,3S)-[Partial]-(9Ci) is a high-purity, stereochemically defined chiral intermediate of significant importance in advanced organic synthesis. This compound matters because it provides a critical building block for the construction of complex molecules, particularly in the pharmaceutical sector where specific stereochemistry is essential for biological activity. Pharmaceutical R&D and fine chemical manufacturers need this precise intermediate for developing active pharmaceutical ingredients (APIs), agrochemicals, and other specialty chemicals. Its defined (2S,3S) configuration ensures consistency and reliability in downstream synthetic pathways.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly for complex therapeutic agents.
• Agrochemical Synthesis: Used in the production of advanced, stereoselective pesticides and herbicides where specific isomer activity is required.
• Fine Chemical Manufacturing: Serves as a versatile building block for synthesizing specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic & Industrial Research: A valuable reagent in methodological development for asymmetric synthesis and catalysis studies within R&D laboratories.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial production of stereochemically complex molecules.

Basic Information

Product Name	2H-Pyran-2-Methanol,6-Ethoxytetrahydro-3-Methyl-,Acetate,(2S,3S)-[Partial]-(9Ci)
CAS No.	190014-74-5
Molecular Formula	C11H20O4
Molecular Weight	216.27 g/mol
Synonyms	(2S,3S)-6-Ethoxy-3-methyltetrahydro-2H-pyran-2-yl)methyl acetate; (2S,3S)-6-Ethoxy-3-methyltetrahydro-2H-pyran-2-ylmethyl acetate; (2S-cis)-6-Ethoxy-3-methyltetrahydro-2H-pyran-2-methanol acetate; Acetic acid (2S,3S)-6-ethoxy-3-methyltetrahydro-2H-pyran-2-ylmethyl ester; Tetrahydro-6-ethoxy-3-methyl-2H-pyran-2-methanol, acetate, (2S,3S)-; A chiral tetrahydropyranyl acetate derivative.
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality control protocols to ensure batch-to-batch consistency and high stereochemical purity, which is critical for pharmaceutical applications. Quality is verified through advanced analytical techniques including Chiral HPLC to confirm enantiomeric excess and NMR for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is likely light-sensitive and should be handled under an inert atmosphere if prolonged exposure is anticipated to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.