Description

C-(2,3,4-Tri-o-Acetyl-1-Azido-1-Deoxy-β-D-Arabinopyranosyl) Formamide is a specialized, high-purity carbohydrate derivative and a key synthetic intermediate in nucleoside chemistry. This compound is critical for the development of novel antiviral and anticancer agents, where precise stereochemistry and functional group manipulation are paramount. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and advanced academic research institutions engaged in the synthesis of modified nucleosides and oligonucleotides.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel arabinonucleoside analogs with potential antiviral and anticancer activities.
• Antiviral Drug Research: Used in the development of nucleoside reverse transcriptase inhibitors (NRTIs) and other antiviral compounds targeting viral polymerases.
• Oligonucleotide Synthesis: Serves as a protected arabinose precursor for the preparation of modified oligonucleotides for antisense and siRNA therapeutic applications.
• Chemical Biology Probes: Employed in the creation of metabolic probes and labeled nucleosides for studying cellular processes and enzyme mechanisms.
• Glycochemistry Research: A valuable substrate for studying glycosylation reactions and synthesizing complex carbohydrate structures.
• Process Development: Used in scale-up and optimization studies for the commercial production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	C-(2,3,4-Tri-o-Acetyl-1-Azido-1-Deoxy-β-D-Arabinopyranosyl) Formamide
CAS No.	189633-67-8
Molecular Formula	C₁₂H₁₆N₄O₇
Molecular Weight	328.28 g/mol
Synonyms	1-Azido-1-deoxy-2,3,4-tri-O-acetyl-β-D-arabinopyranosyl Formamide; β-D-Arabinopyranosyl Formamide, 1-azido-1-deoxy-2,3,4-tri-O-acetyl-; 2,3,4-Tri-O-acetyl-1-azido-1-deoxy-β-D-arabinopyranosyl Formamide; 1-Azido-2,3,4-tri-O-acetyl-1-deoxy-β-D-arabinopyranosyl Formamide; Arabinose Azido Acetate Formamide Derivative; CAS 189633-67-8
EINECS	Contact for details

Quality Control

Our C-(2,3,4-Tri-o-Acetyl-1-Azido-1-Deoxy-β-D-Arabinopyranosyl) Formamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.