Description

n-[(5S)-3-(3-Fluoro-4-Trimethylstannanylphenyl)-2-Oxo-Oxazolidin-5-Ylmethyl]Acetamide is a high-purity, organotin-containing oxazolidinone derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in its precise stereochemistry and functional groups, which are essential for constructing complex bioactive molecules in medicinal chemistry. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in the areas of antibacterial and antiviral drug discovery.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel oxazolidinone-class antibiotics and other investigational drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Organometallic Chemistry: Serves as a precursor or reagent in reactions leveraging the trimethylstannyl group for cross-coupling (e.g., Stille reaction) or other organometallic transformations.
• Process Chemistry Development: Employed in scaling up and optimizing synthetic routes for active pharmaceutical ingredients (APIs) under GMP-like conditions.
• Bioconjugation & Probe Synthesis: Potential use in creating labeled compounds or chemical probes for biochemical and pharmacological studies.

Basic Information

Product Name	n-[(5S)-3-(3-Fluoro-4-Trimethylstannanylphenyl)-2-Oxo-Oxazolidin-5-Ylmethyl]Acetamide
CAS No.	188975-86-2
Molecular Formula	C15H21FN2O3Sn
Molecular Weight	423.04 g/mol
Synonyms	(5S)-N-[[3-[3-Fluoro-4-(trimethylstannyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide; Acetamide, N-[(5S)-3-[3-fluoro-4-(trimethylstannyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-; Linezolid Impurity Sn; Linezolid Stannyl Intermediate; (S)-N-((3-(3-Fluoro-4-(trimethylstannyl)phenyl)-2-oxooxazolidin-5-yl)methyl)acetamide; Organotin Oxazolidinone Derivative; Trimethyltin-Linezolid Intermediate
EINECS	Contact for details

Quality Control

Our n-[(5S)-3-(3-Fluoro-4-Trimethylstannanylphenyl)-2-Oxo-Oxazolidin-5-Ylmethyl]Acetamide is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. All batches are characterized by advanced analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Tin (Sn) Content	Theoretical range

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.