Description

(S,S)-(+)-N,N'-Bis(3,5-Di-tert-Butylsalicylidene)-1,2-Cyclohexanediamino-Cobalt(II) is a high-purity, chiral salen-type cobalt complex widely recognized for its exceptional catalytic activity in asymmetric synthesis. This compound matters as a highly efficient and selective catalyst for critical organic transformations, enabling the production of enantiomerically pure intermediates. It is primarily needed by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and fine chemical industries for developing and manufacturing advanced chiral molecules.

Application

• Asymmetric Catalysis: A premier catalyst for enantioselective reactions such as hydrolytic kinetic resolution (HKR) of epoxides.
• Pharmaceutical Intermediates: Synthesis of chiral building blocks and active pharmaceutical ingredients (APIs) requiring high enantiomeric excess (ee).
• Agrochemical Synthesis: Production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Manufacture of specialty chemicals, flavors, and fragrances where optical purity is critical.
• Polymer Science: Catalyst for the synthesis of chiral polymers and materials with specific stereochemical properties.
• Academic & Industrial Research: A valuable tool for methodological development in organic and organometallic chemistry.

Basic Information

Product Name	(S,S)-(+)-N,N'-Bis(3,5-Di-tert-Butylsalicylidene)-1,2-Cyclohexanediamino-Cobalt(II)
CAS No.	188264-84-8
Molecular Formula	C44H58CoN2O2
Molecular Weight	705.87 g/mol
Synonyms	(S,S)-(-)-1,2-Bis(2-hydroxy-3,5-di-tert-butylbenzylideneamino)cyclohexane Cobalt(II); (S,S)-Jacobsen's Cobalt Catalyst; Cobalt(II) (S,S)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediamine; (S,S)-Co(salen); (S,S)-Co(III)(salen) complex precursor; (S,S)-Cobalt Salen Complex; (S,S)-HKR Catalyst; Cobalt(II)-(S,S)-1,2-Diaminocyclohexane-N,N'-bis(3,5-di-tert-butylsalicylidene)
EINECS	Contact for details

Quality Control

Our (S,S)-(+)-N,N'-Bis(3,5-Di-tert-Butylsalicylidene)-1,2-Cyclohexanediamino-Cobalt(II) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot is analyzed to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing specific test results are provided and available upon request, supporting compliance with internal specifications for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. Due to its hygroscopic and easily oxidized nature, the container must be sealed immediately after use to minimize exposure to moisture and air. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Dark brown to black crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (ee)	≥ 99.0%
Metal Content (Co)	7.8 - 8.5%
Solubility	Soluble in common organic solvents (e.g., Toluene, DCM)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.