Description

2H-1-Benzopyran-4-Amine,3,4-Dihydro-,(4S)-(9Ci) is a chiral, high-purity chemical intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key building block in the development of enantiomerically pure pharmaceuticals and bioactive molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, particularly those targeting neurological and cardiovascular pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of active pharmaceutical ingredients (APIs) for central nervous system (CNS) and cardiovascular drugs.
• Asymmetric Synthesis: Utilized as a starting material or reagent in catalytic asymmetric reactions to construct complex molecular architectures with high stereoselectivity.
• Medicinal Chemistry Research: Employed in drug discovery programs for the design and synthesis of new chemical entities (NCEs) and compound libraries for biological screening.
• Process Chemistry Development: Used in the scale-up and optimization of synthetic routes for potential drug candidates during preclinical and clinical development phases.
• Chemical Biology Probes: Acts as a scaffold for developing molecular probes to study enzyme mechanisms and biological pathways.

Basic Information

Product Name	2H-1-Benzopyran-4-Amine,3,4-Dihydro-,(4S)-(9Ci)
CAS No.	188198-38-1
Molecular Formula	C9H11NO
Molecular Weight	149.19 g/mol
Synonyms	(4S)-3,4-Dihydro-2H-1-benzopyran-4-amine; (S)-3,4-Dihydro-2H-chromen-4-amine; (S)-Chroman-4-amine; (4S)-Chroman-4-amine; (S)-4-Aminochroman; (4S)-4-Amino-3,4-dihydro-2H-1-benzopyran; (S)-3,4-Dihydro-2H-1-benzopyran-4-amine; (9CI)
EINECS	Contact for details

Quality Control

Our production of 2H-1-Benzopyran-4-Amine,3,4-Dihydro-,(4S)-(9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. All materials are characterized by advanced analytical techniques including HPLC, GC, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.