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1-Naphthalenemethanamine,5-Ethoxy-1,2,3,4-Tetrahydro-n-Methyl-,(R)-(9Ci) CAS NO 188111-22-0


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CAS No.:188111-22-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-Naphthalenemethanamine,5-Ethoxy-1,2,3,4-Tetrahydro-n-Methyl-,(R)-(9Ci) is a high-purity chiral amine building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of enantiomerically pure pharmaceuticals and agrochemicals, where stereochemical control is critical for biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and complex molecular architectures.

Application

  • Pharmaceutical Intermediate: Serves as a critical chiral synthon in the synthesis of potential drug candidates, particularly for central nervous system (CNS) agents and other therapeutic molecules requiring specific stereochemistry.
  • Agrochemical Synthesis: Used in the research and development of enantiomerically pure herbicides, fungicides, and insecticides, where the (R)-configuration may confer desired biological selectivity.
  • Catalyst and Ligand Development: Acts as a precursor for the synthesis of novel chiral ligands and organocatalysts used in asymmetric synthesis.
  • Fine Chemical and Specialty Chemical Production: Employed in the manufacture of complex, high-value chemicals for electronics, materials science, and other advanced technology sectors.
  • Academic and Industrial Research: A valuable compound for methodological studies in organic chemistry, including new reaction development and stereoselective synthesis.

Basic Information

Item Details
Product Name 1-Naphthalenemethanamine,5-Ethoxy-1,2,3,4-Tetrahydro-n-Methyl-,(R)-(9Ci)
CAS No. 188111-22-0
Molecular Formula C₁₄H₂₁NO
Molecular Weight 219.32 g/mol
Synonyms (R)-5-Ethoxy-1,2,3,4-tetrahydro-N-methyl-1-naphthalenemethanamine; (R)-N-Methyl-1-(5-ethoxy-1,2,3,4-tetrahydronaphthalen-1-yl)methanamine; 1-Naphthalenemethanamine, 5-ethoxy-1,2,3,4-tetrahydro-N-methyl-, (R)-; (R)-1-((5-Ethoxy-1,2,3,4-tetrahydronaphthalen-1-yl)methyl)-N-methylamine; (R)-N-Methyl-1-(5-ethoxy-1,2,3,4-tetrahydronaphthalen-1-yl)methylamine; (R)-5-Ethoxy-N-methyl-1,2,3,4-tetrahydronaphthalen-1-ylmethanamine
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Quality Control

Our 1-Naphthalenemethanamine,5-Ethoxy-1,2,3,4-Tetrahydro-n-Methyl-,(R)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with exacting research and process development standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item Specification
Appearance Colorless to pale yellow liquid or solid
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 97.0%
Chiral Purity (Chiral HPLC) ≥ 98.0% ee (R)
Related Substances (HPLC) Total impurities ≤ 3.0%
Any single unknown impurity ≤ 1.0%
Residual Solvents (GC) Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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