Description

(2R,4R)-2-Phenyl-Tetrahydro-2H-Pyran-4-Ol CAS NO 188053-98-7 is a high-purity chiral building block and pharmaceutical intermediate characterized by its specific stereochemistry. This compound matters for its role in the synthesis of complex molecules where precise three-dimensional structure is critical for biological activity and efficacy. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Synthesis: Used as a versatile chiral auxiliary or starting material in stereoselective organic synthesis to construct complex molecular architectures.
• Agrochemical Research: Serves as a building block for developing new chiral pesticides and herbicides with enhanced specificity and environmental profiles.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & Process Chemistry: A valuable reagent for methodological studies in catalysis and the development of new synthetic routes in university and industrial R&D labs.

Basic Information

Product Name	(2R,4R)-2-Phenyl-Tetrahydro-2H-Pyran-4-Ol
CAS No.	188053-98-7
Molecular Formula	C11H14O2
Molecular Weight	178.23 g/mol
Synonyms	(2R,4R)-2-Phenyl-4-hydroxytetrahydropyran; (2R,4R)-2-Phenyltetrahydro-2H-pyran-4-ol; (2R,4R)-4-Hydroxy-2-phenyltetrahydropyran; 2-Phenyltetrahydropyran-4-ol (2R,4R)-; (2R-cis)-2-Phenyl-4-hydroxytetrahydropyran; cis-2-Phenyl-4-hydroxytetrahydropyran; (2R,4R)-2-Phenyl-4-hydroxy-tetrahydropyran
EINECS	Contact for details

Quality Control

Our (2R,4R)-2-Phenyl-Tetrahydro-2H-Pyran-4-Ol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.