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6-Iodopyridazin-3-Amine CAS NO 187973-60-0
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CAS No.:187973-60-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
6-Iodopyridazin-3-Amine is a versatile halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its dual functionality, featuring both a reactive iodine atom and an amine group, which enables its use in cross-coupling reactions and as a precursor for more complex nitrogen-containing scaffolds. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the discovery and synthesis of novel active ingredients.
Application
- Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
- Agrochemical Research: Serves as a building block for synthesizing novel herbicides, fungicides, or insecticides with potential new modes of action.
- Material Science: Used in the synthesis of specialized ligands, organic semiconductors, or photoactive materials for electronic applications.
- Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, or Buchwald-Hartwig amination to create diverse biaryl and functionalized structures.
- Chemical Biology Probes: Can be utilized to create tagged molecules or affinity probes for studying biological pathways and target engagement.
- Academic & Contract Research: Essential for fundamental research in heterocyclic and organoiodine chemistry within university and CRO (Contract Research Organization) laboratories.
Basic Information
| Product Name | 6-Iodopyridazin-3-Amine |
| CAS No. | 187973-60-0 |
| Molecular Formula | C4H4IN3 |
| Molecular Weight | 221.00 g/mol |
| Synonyms | 3-Amino-6-iodopyridazine; 6-Iodo-3-pyridazinamine; 6-Iodopyridazin-3-ylamine; 3-Pyridazinamine, 6-iodo-; 6-Iodo-3-aminopyridazine; 3-Amino-6-iodo-1,2-diazine; 6-Iodopyridazin-3-amine (IUPAC); 6-Iodo-1,2-diazin-3-amine |
| EINECS | Contact for details |
Quality Control
Our 6-Iodopyridazin-3-Amine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maximize stability.
Specification
| Item | Specification |
|---|---|
| Appearance | Off-white to light yellow crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Melting Point | Contact for details |
| Heavy Metals | < 20 ppm |
| Residual Solvents (GC) | Complies with ICH guidelines |
| Water Content (KF) | < 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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