Description

2-Pyrrolidinemethanol, 1-(Dichloroacetyl)-, (S)- (9Ci) is a high-purity, chiral intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a key building block for constructing complex molecules with defined stereochemistry. This compound is essential for research and development in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and fine chemicals requiring precise chiral control.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and production of novel therapeutic agents, including potential central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the development of advanced, stereoselective pesticides and herbicides where specific chirality enhances biological activity and reduces environmental impact.
• Asymmetric Catalysis: Serves as a precursor or ligand in catalytic systems for asymmetric synthesis, enabling the production of enantiomerically pure compounds.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require high stereochemical purity.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.
• Process Chemistry: Used in scale-up and optimization studies for the commercial production of chiral molecules.

Basic Information

Item	Details
Product Name	2-Pyrrolidinemethanol, 1-(Dichloroacetyl)-, (S)- (9Ci)
CAS No.	186887-30-9
Molecular Formula	C7H11Cl2NO2
Molecular Weight	212.07 g/mol
Synonyms	(S)-1-(Dichloroacetyl)-2-pyrrolidinemethanol; (S)-1-(Dichloroacetyl)-2-(hydroxymethyl)pyrrolidine; L-1-(Dichloroacetyl)-2-pyrrolidinemethanol; 1-(Dichloroacetyl)-(2S)-2-pyrrolidinemethanol; (S)-1-(Dichloroacetyl)-2-pyrrolidinylmethanol; 186887-30-9; (S)-Dichloroacetylprolinol; A chiral dichloroacetyl pyrrolidine derivative.
EINECS	Contact for details

Quality Control

Every batch of 2-Pyrrolidinemethanol, 1-(Dichloroacetyl)-, (S)- (9Ci) is produced and tested under a strict quality management system. We ensure compliance with high-purity standards suitable for research and industrial synthesis. Comprehensive testing includes chiral purity (enantiomeric excess), chemical purity (HPLC), and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.