Description

n-Dansyl-N'-Ethylthiourea CAS NO 186661-19-8 is a specialized dansyl-labeled thiourea derivative, serving as a critical reagent in advanced analytical and synthetic chemistry. Its core value lies in its strong fluorescence and selective binding properties, making it an essential tool for detection, labeling, and mechanistic studies. This compound is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and life science sectors for applications ranging from fluorescence-based assays to the development of novel chemical sensors and catalysts.

Application

• Fluorescent Labeling and Probes: Used as a derivatizing agent for the sensitive detection and quantification of amines, thiols, and carbonyl compounds via HPLC or LC-MS.
• Chemical Sensor Development: Acts as a key building block or recognition unit in the synthesis of fluorescent chemosensors for metal ions (e.g., Hg²⁺, Cu²⁺) and anions.
• Pharmaceutical Research: Employed in mechanistic studies and as an intermediate in the synthesis of potential therapeutic agents, particularly those targeting enzyme inhibition.
• Material Science: Utilized in the surface functionalization of nanoparticles and polymers to introduce fluorescent tags for tracking and imaging applications.
• Agrochemical Analysis: Serves as a reagent for the trace analysis of pesticide metabolites and environmental contaminants through fluorescence detection methods.
• Bioconjugation: Facilitates the attachment of fluorescent markers to biomolecules like proteins and peptides for cellular imaging and diagnostic assays.

Basic Information

Product Name	n-Dansyl-N'-Ethylthiourea
CAS No.	186661-19-8
Molecular Formula	C₁₅H₁₉N₃O₂S₂
Molecular Weight	337.46 g/mol
Synonyms	1-(5-Dimethylaminonaphthalene-1-sulfonyl)-3-ethylthiourea; Dansyl Ethylthiourea; N-Dansyl-N'-ethylthiourea; N-(5-Dimethylaminonaphthalene-1-sulfonyl)-N'-ethylthiourea; DETU; 186661-19-8; 1-(5-(Dimethylamino)naphthalene-1-sulfonyl)-3-ethylthiourea
EINECS	Contact for details

Quality Control

Our n-Dansyl-N'-Ethylthiourea is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and spectroscopic methods (NMR, IR, MS) for structural confirmation, to ensure compliance with high-purity research-grade standards. Certificates of Analysis (COA) detailing lot-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment to prevent degradation. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.