Description

1,3-Bis((R)-1-(Naphthalen-1-Yl)Ethyl)-1H Imidazol-3-Ium Chlorid CAS NO 186354-48-3 is a chiral ionic liquid and organocatalyst featuring a unique imidazolium core flanked by bulky, enantiomerically pure naphthyl-ethyl substituents. This compound is valued for its role in facilitating asymmetric synthesis, offering a robust and tunable framework for stereoselective transformations. It is primarily sought by R&D chemists and process development teams in the pharmaceutical and fine chemical industries for the development of novel synthetic pathways.

Application

• Asymmetric Organocatalysis: Employed as a chiral catalyst or catalyst precursor for enantioselective C-C and C-heteroatom bond-forming reactions.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs) requiring high enantiomeric purity.
• Chiral Ionic Liquid Media: Serves as a structured reaction medium or additive to influence stereochemical outcomes in synthesis.
• Ligand for Metal Complexes: Acts as a precursor for chiral N-heterocyclic carbene (NHC) ligands used in transition metal catalysis.
• Material Science Research: Investigated for potential applications in chiral sensing, separation membranes, or advanced polymeric materials.
• Academic & Industrial R&D: A key reagent for methodological development in organic and organometallic chemistry laboratories.

Basic Information

Product Name	1,3-Bis((R)-1-(Naphthalen-1-Yl)Ethyl)-1H Imidazol-3-Ium Chlorid
CAS No.	186354-48-3
Molecular Formula	C₂₉H₂₇ClN₂
Molecular Weight	439.0 g/mol
Synonyms	(R,R)-1,3-Bis(1-(1-Naphthyl)ethyl)imidazolium Chloride; 1,3-Bis[(1R)-1-(1-Naphthyl)ethyl]-1H-imidazol-3-ium Chloride; (R,R)-1,3-Di(1-naphthylethyl)imidazolium Chloride; Chiral Imidazolium Salt; NHC Precursor Salt; Asymmetric Ionic Liquid; 1,3-Bis(1-(Naphthalen-1-yl)ethyl)-1H-imidazol-3-ium Chloride
EINECS	Contact for details

Quality Control

Our production of this advanced chiral compound adheres to stringent quality protocols. Every batch is characterized to confirm identity, chiral purity, and chemical integrity. A comprehensive Certificate of Analysis (COA) is provided, detailing key parameters such as HPLC purity and enantiomeric excess (ee). We support cGMP and ISO compliant documentation for critical applications in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed in a dry environment to prevent moisture absorption, which can affect performance. For long-term storage, consider handling under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.