Description

3-Bromophenylzinc Iodide is a versatile organozinc reagent, a key building block in modern synthetic organic chemistry. Its value lies in enabling highly selective carbon-carbon bond formation, particularly in Negishi cross-coupling reactions, which are crucial for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-purity intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A critical reagent for the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, especially those containing biaryl or substituted phenyl motifs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require specific bromo-substituted aromatic structures.
• Material Science: Serves as a precursor for creating functionalized organic molecules used in organic light-emitting diodes (OLEDs), liquid crystals, and conductive polymers.
• Negishi Cross-Coupling: The primary application is in palladium-catalyzed cross-coupling with various organic electrophiles to form new C-C bonds with high efficiency and selectivity.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fragrances, dyes, and other high-value specialty chemicals.
• Academic & R&D: A valuable tool for methodological development in organic synthesis and for exploring new reaction pathways in laboratory settings.

Basic Information

Product Name	3-Bromophenylzinc Iodide
CAS No.	186000-44-2
Molecular Formula	C6H4BrZnI
Molecular Weight	348.30 g/mol
Synonyms	(3-Bromophenyl)zinc iodide; Zinc, (3-bromophenyl)iodo-; 3-Bromophenylzinc iodide solution; 1-Bromo-3-(iodozincio)benzene; m-Bromophenylzinc iodide; Bromo-3-phenylzinc iodide; Organozinc reagent 3-BrPhZnI
EINECS	Contact for details

Quality Control

Every batch of 3-Bromophenylzinc Iodide is manufactured and tested under strict quality management protocols. We ensure the product meets high-purity standards suitable for demanding synthetic applications, with typical concentrations specified for common solution formats (e.g., 0.5M in THF). A comprehensive Certificate of Analysis (COA) detailing assay, titration results, and impurity profiles is provided with each shipment to guarantee consistency and support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Due to its moisture-sensitive (hygroscopic) and easily oxidized nature, this reagent must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. For solutions, maintain at recommended temperatures (typically 2-8°C for extended storage) and ensure the septum seal remains intact to prevent solvent evaporation and ingress of air or moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution (typical)
Concentration	0.5 M in Tetrahydrofuran (typical, other solvents available)
Assay (Titration)	≥ 95%
Identification (NMR/IR)	Conforms to structure
Water Content (KF)	< 500 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.