Description

3-Chlorophenylzinc Iodide is a versatile organozinc reagent, a key building block in modern synthetic organic chemistry. Its value lies in enabling highly selective carbon-carbon bond formation, particularly in Negishi cross-coupling reactions, which are critical for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-purity intermediates for developing active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial reagent for the synthesis of active pharmaceutical ingredients (APIs) containing a 3-chlorophenyl moiety, enabling the construction of complex drug candidates.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where the 3-chlorophenyl group imparts specific biological activity.
• Negishi Cross-Coupling Reactions: Serves as a superior organometallic partner with aryl, heteroaryl, or vinyl halides for the efficient formation of biaryl and other coupled structures.
• Ligand and Material Science: Employed in the synthesis of specialized ligands for catalysis and as a precursor for functional organic materials and liquid crystals.
• Fine Chemical Production: Facilitates the manufacture of complex fragrance, dye, and specialty chemical intermediates requiring regioselective functionalization.
• Academic & R&D Laboratories: A valuable tool for methodological development and exploring new synthetic pathways in organic and medicinal chemistry research.

Basic Information

Product Name	3-Chlorophenylzinc Iodide
CAS No.	186000-42-0
Molecular Formula	C6H4ClZnI
Molecular Weight	303.84 g/mol
Synonyms	Zinc, (3-chlorophenyl)iodo-; (3-Chlorophenyl)iodozinc; 3-Chlorophenylzinc iodide solution; (3-Chlorophenyl)zinc iodide; m-Chlorophenylzinc iodide; Iodo(3-chlorophenyl)zinc; 1-Chloro-3-(iodozincio)benzene
EINECS	Contact for details

Quality Control

Every batch of our 3-Chlorophenylzinc Iodide undergoes rigorous analytical testing to ensure it meets the stringent requirements of advanced synthetic applications. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as assay, concentration, and impurity profiles. Our quality management system is designed to ensure batch-to-batch consistency and supply reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Due to its moisture-sensitive (hygroscopic) and easily oxidized nature, this reagent must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended storage temperature is 2-8°C for prolonged stability. Handle and dispense using standard air-free techniques (Schlenk line or glovebox) to maintain purity and reactivity.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Concentration	0.5 M in THF (Typical, other solvents available)
Assay (Titration)	≥ 95%
Identification (IR/NMR)	Conforms to structure
Water Content (Karl Fischer)	< 500 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.