Description

2-Fluorophenylzinc Iodide is a highly reactive organozinc reagent, specifically a fluorinated arylzinc halide. This compound is a critical building block in modern synthetic organic chemistry, enabling the efficient and selective formation of carbon-carbon bonds. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of complex fluorinated aromatic compounds.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for Negishi cross-coupling reactions to introduce the 2-fluorophenyl moiety into drug candidate molecules, particularly in the development of active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the construction of novel fluorinated herbicides, fungicides, and pesticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing specialized fluorinated ligands used in homogeneous catalysis and material science applications.
• Advanced Material Precursors: Employed in the synthesis of fluorinated organic semiconductors, liquid crystals, and polymers for electronic and optical devices.
• Custom Chemical Synthesis: Essential for contract research organizations (CROs) and fine chemical manufacturers producing bespoke fluorinated aromatic compounds for client projects.

Basic Information

Product Name	2-Fluorophenylzinc Iodide
CAS No.	186000-41-9
Molecular Formula	C6H4FZnI
Molecular Weight	287.39 g/mol
Synonyms	(2-Fluorophenyl)zinc Iodide; Zinc, (2-fluorophenyl)iodo-; 2-Fluorophenylzinc Iodide Solution; o-Fluorophenylzinc Iodide; 1-Fluoro-2-(iodozincio)benzene; Fluorobenzene-2-zinc Iodide; 186000-41-9; (o-Fluorophenyl)zinc iodide
EINECS	Contact for details

Quality Control

Every batch of 2-Fluorophenylzinc Iodide is manufactured and handled under strict inert atmosphere conditions to ensure stability and reactivity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing assay (by titration), solvent content, and functional reactivity are available upon request. We support cGMP and ISO 9001 compliant manufacturing for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry, well-ventilated place. Due to its highly moisture-sensitive and easily oxidized nature, the container must be kept sealed and handled under inert conditions to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Concentration	0.5 M in Tetrahydrofuran (Typical)
Assay (Titration)	≥ 95%
Identification (IR)	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.