Description

7(1H)-Indolizinone, 1,6,8-Tris(Acetyloxy)Hexahydro-, 7-(o-Methyloxime), 1S-(1.Alpha.,6.Beta.,8.Beta.,8A.Beta.)- is a complex, high-purity organic intermediate with a defined stereochemistry, making it a valuable building block for advanced synthesis. This compound matters for its role in the research and development of novel pharmaceutical agents and fine chemicals, where precise molecular architecture is critical. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create new active ingredients or complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the multi-step synthesis of potential drug candidates, particularly for complex natural product analogs.
• Agrochemical Research: Used in developing new active ingredients for crop protection, leveraging its intricate indolizinone core structure.
• Fine Chemical Synthesis: Acts as a specialized precursor for creating high-value, complex molecules used in catalysis or material science.
• Academic & Institutional R&D: Employed in university and research institute laboratories for methodological studies in organic synthesis and stereochemistry.
• Process Chemistry Development: Utilized for scaling up synthetic routes from milligram to kilogram scale under current Good Manufacturing Practice (cGMP) guidelines for pre-clinical and clinical trial material production.

Basic Information

Product Name	7(1H)-Indolizinone, 1,6,8-Tris(Acetyloxy)Hexahydro-, 7-(o-Methyloxime), 1S-(1.Alpha.,6.Beta.,8.Beta.,8A.Beta.)-
CAS No.	185899-29-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(1S,3aS,4R,6aR)-4-(Acetyloxy)-1-[(1E)-1-(hydroxyimino)ethyl]hexahydro-2H-cyclopenta[b]furan-2-one; 1,6,8-Tri-O-acetyl-7-oxime derivative; Hexahydro-1,6,8-tris(acetyloxy)-7(1H)-indolizinone 7-(O-methyloxime) (1S-cis); 185899-29-0; Indolizinone derivative, tris-acetylated oxime; 7-(O-Methyloxime) indolizinone triacetate; Chiral indolizinone intermediate; Tris-O-acetyl indolizinone oxime
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) are available upon request, detailing specifications such as assay purity and impurity profiles. We support development under quality systems suitable for cGMP applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is likely light-sensitive and may be hygroscopic; therefore, handling under an inert atmosphere and desiccated conditions is recommended for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.