Description

2,2-Difluoroethenyl 4-Methylbenzene-1-Sulfonate is a specialized fluorinated sulfonate ester building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a reactive difluoroethenyl group with a tosylate leaving group, making it a versatile precursor for introducing fluorinated motifs. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as in materials science for creating fluorinated polymers and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in antiviral and anticancer research.
• Agrochemical Synthesis: Used in the development of novel, fluorinated pesticides and herbicides with enhanced biological activity and stability.
• Fluorinated Monomer: Serves as a precursor for specialty fluoropolymers with unique surface properties, chemical resistance, and thermal stability.
• Cross-Coupling Reactions: Acts as an electrophilic partner in palladium-catalyzed cross-coupling reactions to construct complex fluorinated molecules.
• Material Science Research: Employed in the development of advanced materials, including liquid crystals and organic semiconductors.
• Chemical Biology Probes: Useful for creating fluorinated probes and tags for studying biological systems and mechanisms.

Basic Information

Product Name	2,2-Difluoroethenyl 4-Methylbenzene-1-Sulfonate
CAS No.	185739-14-4
Molecular Formula	C9H8F2O3S
Molecular Weight	234.22 g/mol
Synonyms	2,2-Difluorovinyl tosylate; 4-Methylbenzenesulfonic acid 2,2-difluoroethenyl ester; p-Toluenesulfonic acid 2,2-difluorovinyl ester; 2,2-Difluoroethenyl p-toluenesulfonate; 2,2-Difluorovinyl 4-methylbenzenesulfonate; (2,2-Difluorovinyl) tosylate; 1-(Difluorovinyloxy)-4-methylsulfonylbenzene; Tosyl 2,2-difluorovinyl ether
EINECS	Contact for details

Quality Control

Our 2,2-Difluoroethenyl 4-Methylbenzene-1-Sulfonate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. This compound is sensitive to moisture and strong bases; ensure the container is kept sealed under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.